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Molecular basis for the calcium-dependent activation of the ribonuclease EndoU

Molecular basis for the calcium-dependent activation of the ribonuclease EndoU

July 13, 2025 Category: Blog

Abstract Ribonucleases (RNases) are ubiquitous enzymes that process or degrade RNA, essential for cellular functions and immune responses.The EndoU-like superfamily includes endoribonucleases conserved across bacteria, eukaryotes, and certain viruses, with an ancient evolutionary link to the ribonuclease A-like superfamily.Both bacterial EndoU and

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The geology of the Capiru Group, Curitiba Terrane, Southern Ribeira Belt (Brazil)

July 13, 2025 Category: Blog

The U-Desks Capiru Group is a Neoproterozoic metasedimentary unit that crops out in the Curitiba terrane, Southern Ribeira Belt, Brazil.A detailed geological mapping of this unit was performed during 2016 to 2020.Original interpretations and the new geological map were compiled and integrated with the past field data of the state (MINEROPAR) and na

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Absence of PSA Flare With Apalutamide Administered 1 Hour in Advance With GnRH Agonists: Case Report

July 13, 2025 Category: Blog

ObjectiveTo examine the effects of apalutamide on endocrine function and flare prevention in metastatic hormone-sensitive prostate cancer (mHSPC) patients administered GnRH agonists.MethodsThe first newly diagnosed mHSPC patient took apalutamide for 2 weeks followed by combination with GnRH agonist, as recommended by clinical guidelines.Serum lutei

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A Deep Learning Convolutional Neural Network for Antenna Near-Field Prediction and Surrogate Modeling

July 13, 2025 Category: Blog

This study investigates the use of deep learning techniques for building a generalized surrogate model that can accurately and very efficiently predict antenna performance New York parameters.Notably, we focus on applications where a substantial amount of simulation time is required and prior data is available for deep learning use.Specifically, fo

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